Chemistry and Biochemistry
CHEM 211, 212 are prerequisites to all other undergraduate CHEM courses numbered 301 or above.
101 Introduction to Modern Chemistry (3:3:0) Not open to students majoring in chemistry. Credit will not be given for this course and CHEM 103. Fundamental principles of chemistry. Physical and chemical discoveries and properties of matter presented along with their application and impact on way of life. Topics include atomic and molecular structure, nuclear chemistry, and chemistry in Earth and atmosphere. No previous knowledge of chemistry assumed or required.
102 Introduction to Organic and Biological Chemistry (3:3:0) Prerequisite: CHEM 101, 103, or 211. Not open to students majoring in chemistry. Course cannot be used in place of CHEM 313 or 314. Credit will not be given for this course and CHEM 104. Structure and properties of major classes of organic compounds with particular reference to organic molecules and their relationship to manmade polymers and biopolymers including carbohydrates, lipids, proteins, and nucleic acids. Primarily intended for those interested in applying principles of organic chemistry and biochemistry to related areas such as genetics, microbiology, physiology, and nutrition.
103, 104 Chemical Science in a Modern Society (4:3:3) CHEM 103 is a prerequisite for CHEM 104. Not open to students majoring in chemistry. Credit will not be given for both this course and CHEM 211, 212. Terminal course in chemistry for nonscience and nursing majors. Principles and application of chemistry. Topics are those described for CHEM 101 and 102 but with lab to enhance scientific experience.
155, 156 Introduction to Environmental Chemistry I and II (4:3:3) Prerequisite for 156: CHEM 155. Credit will not be given for this course and CHEM 103, 104. Basic chemical principles of Earth's water, air, and soil systems, presented in the context of understanding environmental issues. Includes Saturday morning field trips to sites of past and present environmental contamination, alternating with Saturday morning laboratory activities.
201 Introductory Chemistry I (3:3:0) Does not fulfill degree requirements for laboratory science course. Credit will not be given for this course and CHEM 211 or 103. General chemistry course for students interested in science, engineering, mathematics, or computer science who do not require a lab. Fundamental principles of atomic and molecular structure; chemical bonding; basic concepts of chemical reactions and thermochemistry; and properties of gases, liquids, and solids.
202 Introductory Chemistry II (3:3:0) Prerequisite: CHEM 201 or 211. Does not fulfill degree requirements for laboratory science course. Credit will not be given for this course and CHEM 212 or 104. Second-semester general chemistry course for those interested in science, engineering, mathematics, or computer science who do not require a lab. Fundamentals of reaction rates and equilibrium. Topics include kinetics, properties of solutions, ionic equilibrium, chemical thermodynamics, electrochemistry, and nuclear chemistry.
211, 212 General Chemistry (4:3:3), (4:3:3) CHEM 211 is prerequisite to 212. Credit will not be given for this course and CHEM 103, 104. Basic facts and principles of chemistry, including atomic and molecular structure, gas laws, kinetics, equilibrium, electrochemistry, nuclear chemistry, and properties and uses of the more important elements and their compounds. Students majoring in science, engineering, or mathematics should choose this course sequence.
251 General Chemistry for Engineers (4:3:3) Enrollment restricted to students intending to major in engineering. Students who need two semesters of chemistry should enroll in CHEM 211. Credit will not be given for this course and CHEM 211. Fundamental principles of chemical structure and reactivity including atomic and molecular structure; chemical bonding; structures of ionic, covalent, and metallic lattices; oxidation reduction; electrochemistry and chemistry of metals; and introduction to organic chemistry and polymers.
300 Chemistry of Semiconductor Processing (3:3:0) Prerequisite: completion of 30 credits, or permission of instructor. Does not satisfy chemistry course requirements for BS in biology. Cannot be used as a chemistry elective toward BA, BS, or minor in chemistry, and does not fulfill premedical requirements. Chemical aspects of the manufacture of semiconductor devices. Topics include oxidation of silicon, photoresists, plasma etching, removal of metal contaminants by acid etching, and analysis of semiconductor thin films.
313, 314 Organic Chemistry (3:3:0) Corequisite for CHEM 313: CHEM 315; corequisite for CHEM 314: CHEM 318. CHEM 313 is [prerequisite?] for CHEM 314. Theoretical, synthetic, industrial, and biological aspects of the chemistry of carbon compounds.
315 Organic Chemistry Lab I (2:1:3) Corequisite: CHEM 313. Lab techniques and reactions arranged to accompany CHEM 313. One-hour recitation.
318 Organic Chemistry Lab II (2:1:3) Prerequisite: CHEM 315. Corequisite: CHEM 314. Continuation of CHEM 315, arranged to accompany CHEM 314. One-hour recitation.
321 Elementary Quantitative Analysis (4:2:6) Principles of chemical analysis emphasizing ionic equilibria. Lab consists of gravimetric, volumetric, and instrumental methods illustrating principal types of quantitative determinations.
322 General and Biochemical Equilibrium (2:2:0) Prerequisite: CS 103, 112, or 161. Study of general and biochemical equilibria in gas phase, ionic, and heterogeneous systems. Topics include gas reactions, polyfunctional acids and bases, complexion formation, solubility and free energy relationships, and the use of computer algorithms to solve equilibrium problems.
331, 332 Physical Chemistry I, II (3:3:0) Prerequisite: MATH 113, 114. Prerequisite or corequisite: PHYS 243 or 160. CHEM 331 is prerequisite to 332. Yearlong survey covering topics including thermodynamics, equilibria, kinetics, solution properties, elementary quantum theory, electrochemistry, atomic and molecular structure, and nuclear chemistry.
333, 334 Physical Chemistry for the Life Sciences I, II (3:3:0) Prerequisites: CHEM 211, 212; MATH 113. CHEM 333 is prerequisite to CHEM 334. Corequisite or prerequisite: MATH 114. Credit will not be given for both this course sequence and CHEM 331, 332. Yearlong survey of principles of physical chemistry emphasizing application in biological sciences. Topics include first and second laws of thermodynamics, free energy and chemical equilibria, kinetics, transport properties, molecular interactions, molecular structure, spectroscopy, statistical thermodynamics, and x-ray diffraction.
336 Physical Chemistry Lab I (2:1:3) Prerequisite or corequisite: CHEM 331 or 333. Quantitative experimental study of physicochemical principles. CHEM 336 and 337 constitute an introduction to the practice and theory of experimental physical chemistry. One-hour recitation.
337 Physical Chemistry Lab II (2:1:3) Prerequisite or corequisite: CHEM 332 or 334. Continuation of CHEM 336. One-hour recitation.
341 Fundamental Inorganic Chemistry (3:3:0) Descriptive chemistry including chemical properties, reactions, and reaction mechanisms of inorganic elements and compounds. Topics include main group and transition elements, organometallic compounds, and bioinorganic chemistry.
350 Computer Techniques for Chemistry (3:3:0) Prerequisite: CHEM 313. Introduction to computer software, both commercial and online, emphasizing applicability to chemistry topics. Techniques include spreadsheet programming, graphing and statistics, molecular modeling, and chemical information search and retrieval.
401 The Research Experience (3:1:6) Prerequisites: completion or concurrent enrollment in all other required general education courses. Introduction to research on current problem in chemical sciences, under supervision of faculty advisor. Includes literature search, writing research proposal, attendance at scheduled seminars, written report including impact statement, and oral presentation.
422 Instrumental Analysis (3:3:0) Prerequisites: CHEM 314, 321, and 331. Introduces theories of analysis by instrumental methods. Basic electronics applied to chemical measurements. Topics include introduction to theory of spectroscopy including ultraviolet, visible, and infrared, and electrochemical methods of analysis; theory of Fourier transform techniques such as FT-IR and FT-NMR; and theory of advanced pulse techniques.
423 Instrumental Analysis Laboratory (2:0:6) Prerequisite: CHEM 422. Laboratory-based introduction to quantitative analysis of organic and inorganic substances by using modern analytical instrumentation. Laboratory highlights practice of atomic and molecular spectroscopy, spectrophotometry, chromatography, voltammetry, and potentiometry in relation to chemical experimentation.
441 Properties and Bonding of Inorganic Compounds (3:3:0) Prerequisites: CHEM 314 and 332. Interpretation of physical and chemical properties of inorganic compounds in terms of currently used bonding concepts. Topics include molecular symmetry and applications of symmetry, structure and bonding in ionic solids; and stereochemical, electronic, and magnetic properties of transition metal complexes and metal atom cluster compounds.
445 Inorganic Preparations and Techniques (2:0:6) Prerequisites: CHEM 321 and 441. Application of techniques of inorganic chemistry to preparation, purification, and spectroscopic characterization of selected substances.
446 Bioinorganic Chemistry (3:3:0) Prerequisite: CHEM 314. Application of inorganic coordination chemistry and physical methods in study of structure and function of metal ion sites in biomolecules. Properties of transition metal ions, ligand field theory. Topics include iron cytochromes, zinc and copper enzymes, cobalamins, iron sulfur proteins, oxygen transport, iron storage, electron transfer, inorganic model compounds, metals in medicine, and toxicity of inorganic species.
451, 452 Special Projects in Chemistry (2:0:6) Prerequisites: Chemistry major or minor, 90 credits, and permission of department research committee. Introduction to chemical research or development. Includes literature search, conferences, and lab. Written and oral technical reports required.
455, 456 Honors Research in Chemistry (3:1:6) Prerequisites: CHEM 313, 314, 321, 331-332 or 333-334; admission to Chemistry Department Honors Program; and permission of department research committee. Credit will not be given for both these courses and CHEM 451, 452. Introduction to research on current problem in chemical sciences under supervision of faculty advisor. Includes literature search, laboratory or theoretical work, conferences with faculty advisor, attendance at regularly scheduled seminars, and oral and written presentations.
463 General Biochemistry I (4:4:0) Prerequisites: CHEM 313, BIOL 213. Brief introduction to biochemistry, followed by in-depth look at amino acids and proteins, 3-D structure, folding and dynamics, and specialized function. Emphasizes enzymes and their chemical mechanisms, and metabolism.
464 General Biochemistry II (3:3:0) Prerequisite: CHEM 463/BIOL 483. Continuation of general biochemistry, focusing on secondary metabolism, cell signaling, and processes of replication, transcription, and translation. Emphasizes important biochemistry research topics; much material drawn from current biochemical literature.
465 Biochemistry Lab (2:0:6) Corequisite: CHEM 463. Introduction to modern biochemical experimental methods of studying chemical and physical properties of biological molecules. Includes separation, identification, and characterization of biomolecules.
467 The Chemistry of Enzyme-Catalyzed Reactions (3:3:0) Prerequisites: CHEM 313 and 463. Examples of enzyme mechanisms demonstrate how chemical principles are employed by living organisms. Specific enzyme mechanisms used to illustrate principles from organic, inorganic, and physical chemistry. Discusses techniques to monitor enzyme reactions.
468 Bioorganic Chemistry (3:3:0) Prerequisites: CHEM 314 and 463. Basic understanding of chemical nature of biomolecules and biomacromolecules. Introduces biomolecules such as amino acids, proteins, carbohydrates, and lipids. Lectures focus on biophysical properties and synthesis, using practical examples and visual aids.
470 Laboratory Instructional Methods for Chemistry (3:1:6). Prerequisite: CHEM 314. Lecture and laboratory experience teaching chemistry in laboratory. Students work closely with faculty member and are responsible for all aspects of teaching undergraduate laboratory techniques. Students also learn techniques for acquisition and storage of chemicals and laboratory apparatus, safety, disposal of chemical waste, and literature of chemical education.
500 Selected Topics in Modern Chemistry (3:3:0) Topics of interest in analytical, biological, environmental, geological, geochemical, inorganic, organic, and physical chemistry. May be repeated for credit with different topics. Credit not allowed toward major in chemistry.
505 Hazardous Materials Waste Management (1-3: 1-3:0) Prerequisite: CHEM 313 or permission of instructor. Comprehensive review of subjects most frequently encountered in hazardous chemicals management.
513 Synthetic and Mechanistic Organic Chemistry (3:3:0) Prerequisites: CHEM 313 and 314. General review of synthetic pathways and applications to new topics, emphasizing fused ring aromatics, heterocyclics, natural products, and biologically active compounds. Includes relationship of applied organic chemistry to consumer products, including drugs and agricultural chemicals. Organic core course.
521 Theory of Analytical Processes (3:3:0) Prerequisite: CHEM 422 or permission of instructor. Theory of signal and noise, mass transport phenomena, thermodynamics, and ionics in analytical chemistry. Applications made to Fourier transform techniques such as FT-IR and FT-NMR, convolution and correlation spectroscopy, chemical sensors, chromatography, flow injection analysis, ion transport in membrane, and interpretation of analytical signals. Analytical core course.
529 Instrumental Techniques of Analysis (2:0:6) Prerequisites: CHEM 321 and 422 or 521, or permission of department. Principles and operation of modern instrumentation, emphasizing applications to analysis of chemical, biological, and environmental samples. Methods include combined capillary column gas chromatography and mass spectrometry, high-performance liquid chromatography, optical methods, surface analysis methods, magnetic resonance spectroscopy, atomic emission and absorption spectrometry, and electroanalytical methods. With approval of research committee, students choose methods studied.
531 Elements of Physical Chemistry (3:3:0) Prerequisite: CHEM 314; PHYS 243, 245; and MATH 113; or permission of instructor. Intensive overview of concepts, techniques, and models of physical chemistry as they apply in many branches of chemistry and allied sciences. Topics include properties of gases, first and second laws of thermodynamics, phase and chemical equilibrium, chemical kinetics, atomic and molecular structure, and spectroscopy. Emphasizes developing practical skill in using tools of physical chemistry. Extensive use of spreadsheet models to investigate chemical and physical systems.
554 Geochemistry of Environmental Hazards (3:2:3) Prerequisite: CHEM 314 or permission of instructor. Introduction to origins and reactions of hazardous substances in air, water, and soil environments. Covers movement of trace organic and inorganic substances in geochemical cycle, with particular reference to transport processes that influence air and water quality.
579 Special Topics (1-6:1-6:0) Prerequisites: CHEM 314 or permission of instructor. Current topics in chemistry, depending on instructor's specialty. May be repeated with different topics, with department approval.
613 Modern Polymer Chemistry (3:3:0) Prerequisite: CHEM 513 or permission of instructor. Synthetic and analytical chemistry of synthetic macromolecules. Topics include polymer solutions, molecular weight determination, spectroscopy, thermal analysis, x-ray crystallinity, polymerization types, and commercial and electroactive polymers.
614 Physical Organic Chemistry (3:3:0) Prerequisite: CHEM 314 or permission of instructor. Principles underlying molecular structure, reactivity, and reaction mechanisms. Topics include valence-bond and molecular-orbital theory, electronic interpretation of organic reactions, stereochemistry, conformational analysis, kinetics and thermodynamics of organic reactions, and photochemistry. Organic core course.
617 Organic Structural Spectroscopy (3:3:0) Prerequisite: CHEM 314 or equivalent. Spectroscopic determination of organic molecular structure using 1H, 13H, 19F, and 31P nuclear magnetic resonance spectroscopy and infrared, mass, ultraviolet and visible, and Raman spectroscopy.
620/PHYS 533 Modern Instrumentation (3:2:2) Prerequisite: CHEM 422 or permission of instructor. Methods of sensing and measurement of radiation, particles, pressure, concentrations of specific elements and compounds. Topics include basic operational amplifier circuits for analog signals, digitizing devices and computerized data collection, noise and noise-reduction methods, and specialized instrumentation systems for various areas of chemistry and physics.
624 Principles of Chemical Separation (3:3:0) Prerequisite: CHEM 422 or 521, or permission of instructor. Theories and models of separation with applications to analyses of a wide range of chemical, biological, and environmental samples. Topics include high-resolution gas and high-performance liquid chromatography. Emphasizes theory of reverse phase, normal phase, ion exchange, size exclusion, and affinity based separations. Also presents instrumentation such as detectors, pumps, and columns, and data acquisition. Analytical core course.
625 Electroanalytical Chemistry (3:3:0) Prerequisites: CHEM 321 and 331. Review of basic electrochemistry. Emphasizes analysis and research for applications of modern electrochemical techniques such as chronoamperometry; cyclic, stripping, and AC voltammetry; pulse polarography; coulometry; electrochemical sensors; and instrumentation.
633/CSI 711 Chemical Thermodynamics and Kinetics (3:3:0) Prerequisites: CHEM 331 and 332. Advanced study covering application of kinetics to the elucidation of reaction mechanisms, and application of statistical thermodynamics to theory of elementary reaction rates. Physical core course.
646 Bioinorganic Chemistry (3:3:0) Prerequisite: CHEM 441 or permission of instructor. Applies inorganic coordination chemistry and physical methods to understand structure and function of metal ion sites in biomolecules. Biochemical roles of metal centers in oxygen transport, metalloenzymes, and electron transfer. Topics include iron cytochromes, zinc and copper enzymes, cobalamins, iron sulfur proteins, inorganic model compounds, and metals in medicine. Inorganic core course.
651 Environmental Chemistry of Organic Chemicals (3:3:0) Prerequisite: one semester of physical chemistry, or permission of instructor. Study of principles governing multimedia distribution and fate of organic chemicals in environment. Overview of origin and occurrence of major classes of natural and anthropogenic organic chemicals in environment. Environmental core course.
563, 564 Biochemistry (3:3:0) Prerequisites: CHEM 313 and 314. CHEM 663 is prerequisite to CHEM 664. Previous course in biology recommended but not required. CHEM 663 is the biochemistry core course. Important biological compounds, including proteins, carbohydrates, lipids, and nucleic acids, and their interrelations.
670 Teaching Practicum (1-2:0:0) Prerequisites: enrollment in graduate program and demonstrated proficiency in English language. Prelaboratory lecture and laboratory teaching in chemistry. Students work closely with faculty and are responsible for all aspects of teaching undergraduate laboratory techniques.
690 Graduate Seminar (1:1:0) Prerequisite: attendance at minimum 70 percent of departmental seminars in semester preceding each enrollment. Selected topics from recent chemical theory and applications, designed to inform about current developments in chemical sciences. Requires, in last semester, seminar presentation on student's research or another topic acceptable to department. Three credits of CHEM 690 required for MS degree; an additional 3 credits required after admission to PhD program.
728/CSI 712 Introduction to Solid Surfaces (3:3:0) Prerequisite: CHEM 422 or equivalent. Introduces properties of solid surfaces. Topics include gas adsorption isotherms, surface area measurement techniques, real and clean surfaces, physisorption and chemisorption, methods of gas adsorption and desorption, measurement of heats of adsorption, desorption kinetics, electron spectroscopies and surface sensitivities, instrumentation; and principles of vacuum technology.
730/CSI 782/PHYS 711 Statistical Mechanics (3:3:0) Prerequisite: permission of instructor. Statistical methods, systems of particles, thermodynamics, macroscopic parameters, the ideal gas, kinetic theory, quantum statics, and transport processes.
732/CSI 713 Quantum Chemistry (3:3:0) Prerequisite: CHEM 332. Illustration of fundamental concepts of quantum mechanics with applications to chemical systems, including atomic and molecular electronic structure and properties, molecular symmetry, and intermolecular forces. Physical core course.
733 Polymer Physical Chemistry (3:3:0) Prerequisite: CHEM 332 or permission of instructor. Physical chemistry of macromolecules including molecular weight, conformation, configuration, characteristics of the glassy state, methods for studying polymer morphology (XRD, SEM, TEM, optical microscopy), electronic structure and behavior, band theory, conduction mechanisms, intrinsically conductive polymers, polarization, dielectric behavior, triboelectric behavior, piezo and pyroelectric behavior, and nonlinear optical properties.
736/CSI 783/PHYS 736 Computational Quantum Mechanics (3:3:0) Prerequisite: PHYS 502, 510, or permission of instructor. Study of fundamental concepts of quantum mechanics from computational point of view, review of systems with spherically symmetric potentials, electronatom solutions to Schroedinger's equation, electron spin in many electron systems, atomic structure calculations, algebra of many electron calculations, Hartree-Fock, self-consistent field method, molecular structure calculations, scattering theory computations, and solid-state computations.
798 Research Project (3-6:0:0) Prerequisites: permission of department; 6 credits of CHEM 798 or 799, but credit will not be given for both. Experimental or theoretical research project chosen and completed under guidance of graduate faculty member. Requires comprehensive report acceptable to advisory committee, and final oral exam on report. Graded S/NC.
799 Master's Thesis (1-6:0:0) Prerequisite: permission of department. Laboratory thesis research and writing under direction of supervisor. Minimum of 3 credits for first two enrollment periods. Graded S/NC.