University Catalog: 2008-09

Think. Learn. Succeed.

Biology (BIOL)

Molecular and Microbiology

103 Introductory Biology I (4:3:3) Survey course suitable for any major. Topics include chemistry of life, cell structure and function, Mendelian genetics, evolution, and diversity of life. May not be taken after BIOL 200 level or above courses have been taken. f, sum

104 Introductory Biology II (4:3:3) Students are strongly urged to take BIOL 103 prior to BIOL 104. Survey course suitable for any major. Topics include animal (including human) structure, function, homeostatic mechanisms, organ systems, behavior, higher plant systems, and major concepts in ecology. May not be taken after BIOL 200 level or above courses have been taken. sp, sum

105 Introductory Biology I Laboratory (1:0:3)Prerequisite: Permission of BIOL 103/104 coordinator and department chair. Not available to students who have taken BIOL 103 or the equivalent. The chemical basis of life, the structure and function of the cell, Mendelian and human genetics, and the major animal phyla are presented.

106 Introductory Biology II Laboratory (1:0:3)Prerequisite: Permission of BIOL 103/104 coordinator and department chair. Not available to students who have taken BIOL 104 or the equivalent. The structure and function of major organ systems of animals and an examination of the structure and function of plants, emphasizing the higher plants.

124, 125 Human Anatomy and Physiology (4:3:3), (4:3:3) Must be taken in sequence. Does not satisfy natural science requirement for BA in CAS. Introduction to structure and function of body’s major organ systems. f,s,sum

213 Cell Structure and Function (4:3:3) For science majors and preprofessionals in life sciences. Introduction to cell chemistry, metabolism, and genetics. f,s,sum

225 Human Reproduction and Sexuality (3:3:0) Not available for biology major or minor credit. Examines anatomy and physiology of human reproductive systems, physiology of sexual intercourse, normal pregnancy, birth, congenital conditions, sex determination and its expression, diseases of reproductive organs, and technical developments related to reproduction. f

246 Introductory Microbiology (3:3:0) Prerequisite: C or better in BIOL 124 and 125, one year of general biology, or permission of instructor. Corequisite: BIOL 306. Not available for biology major credit. Not available to students who have taken BIOL 213 or 418. Introduction to microbial cell structure, physiology, and pathogenicity. Emphasizes control of microorganisms, host-parasite interactions including immunology, and viral and bacterial pathogens. f,s

301 Biology and Society (3:3:0) Prerequisites: BIOL 103 and 60 credits, or permission of instructor. Not available for biology major or minor elective credit. Biological problems facing society including pollution, cloning, emerging diseases, global warming, and overpopulation. See Schedule of Classes for current topic; may be repeated if topic is different.

303 Animal Biology (4:3:3) Prerequisite: C or better in BIOL 213, or permission of instructor. Emphasizes structure and function of vertebrates, but surveys all animal groups and protozoa. Also covers evolutionary theory, and evolutionary history of major animal groups. f,s,sum

304 Plant Biology (4:3:3) Prerequisite: C or better in BIOL 213, or permission of instructor. Introduction to study of plants, their structure, development, nutrition, and ecology. Emphasizes flowering plants, but surveys all groups and their phylogenetic relationships. f,s,sum

305 Biology of Microorganisms (3:3:0) Prerequisite: C or better in BIOL 213, or permission of instructor. Corequisite: BIOL 306. Morphology, physiology, and pathogenicity of certain groups of bacteria, fungi, and viruses; stresses host-parasite interactions. f,s,sum

306 Biology of Microorganisms Laboratory (1:0:3) Corequisite: BIOL 246 or 305. Laboratory techniques in culturing, staining, and identifying microorganisms. f,s,sum

307 Ecology (4:3:3) Prerequisites: BIOL 303 and 304, or permission of instructor. Physical environment, energy flow, structure and function of populations, dynamics of communities, and succession. f,s,sum

309/GEOL 309 Introduction to Oceanography (3:3:0) Prerequisites: GEOL 101 and BIOL 103, or 213 or EVPP 110, or permission of instructor. Introduction to chemical, biological, and geological aspects of oceanic environment. May include field trip. f

311 General Genetics (4:3:3) Prerequisites: BIOL 213, 303, 304, 305, 306 all completed with no more than one D; or permission of instructor. Basic principles of heredity and modern developments in this field. f,s,sum

312 Biostatistics (4:3:2) Prerequisites: BIOL 303 and 304, or permission of instructor. Use of probability and descriptive and inferential statistical techniques in interpreting biological data. f

313 Human Genetics for the Social Sciences (3:3:0) Prerequisite: one year of biology, or permission of instructor. Not available for biology credit. Emphasizes topics of interest to students in social sciences, but open to any nonbiology major. Topics include human genome and its inheritance; nature versus nurture; genetic disease; genetics of sex determination, intelligence, personality, and mental illness; genetic differences within and between populations; and evolution of human beings. s,odd

318 Conservation Biology (3:3:0) Prerequisites: BIOL 307, 311. Introduction to science used to identify species in need of conservation, and techniques to manage and protect organisms.

320 Comparative Chordate Anatomy (4:2:6) Prerequisite: BIOL 303, or permission of instructor. Compares anatomy and morphology of major chordate groups. Lab emphasizes shark, mudpuppy, cat, and rabbit. af

322 Developmental Biology (4:3:3) Prerequisites: BIOL 303 and 311, or permission of instructor. Principles of embryonic development and differentiation in animal species at cellular, molecular, tissue, and whole organism levels. f

326 Animal Physiology (3:3:0) Prerequisites: BIOL 213, 303, and 60 credits. General consideration of animal function emphasizing common life problems and methods for solving them. Topics include intercellular communication (nervous and endocrine), metabolism, water and solute balance, and cardiovascular and respiratory physiology.

327 Animal Physiology Laboratory (2:1:3) Prerequisites or corequisites: BIOL 326 and permission of instructor. Investigation of invertebrate and vertebrate physiology. Emphasizes responses to environmental changes.

331 Invertebrate Zoology (4:3:3) Prerequisite: BIOL 303, or permission of instructor. Survey of invertebrate phyla, excluding insects, showing morphology, phylogeny, and general biology of these groups.

332 Insect Biology (4:3:3) Prerequisite: BIOL 303, or permission of instructor. Survey of insects including taxonomy, morphology, physiology, behavior, ecology, and economic importance.

333 Vertebrate Zoology (4:2:6) Prerequisite: BIOL 303, or permission of instructor. Phylogeny and systems of major vertebrate groups. Emphasizes ecological adaptation. Lab includes field studies of local fauna.

342 Plant Morphology (4:3:3) Prerequisite: BIOL 304, or permission of instructor. Origin and development of organs, tissue systems, and life cycles of green plants, with phylogenetic comparisons from algae to angiosperms.

344 Taxonomy of Flowering Plants (4:3:3) Prerequisite: BIOL 304, or permission of instructor. Study of terminology and identification of flowering plants with emphasis on local flora.

345 Plant Communities (4:3:3) Prerequisite: BIOL 304, or permission of instructor. Plant associations and formations and their successions in North America. Three Saturday or Sunday field trips required.

350 Freshwater Ecosystems (4:3:3) Prerequisites: CHEM 211/ 212, and either EVPP 110/111 or BIOL 307. Studies physical, chemical, and biological processes in lakes, streams, and wetlands. Lectures, field trips, and lab exercises teach physical and chemical aspects of aquatic systems and life cycles, and adaptations of aquatic organisms.

371 Animal Distributions (3:3:0) Prerequisites: BIOL 303 and 304, or permission of instructor. Relations of North and South American faunas with other regions in light of continental drift. Emphasizes vertebrates.

377 Applied Ecology (3:3:0) Prerequisite: 8 credits of biology, geology, or chemistry; 60 credits; or permission of instructor. Introduction to ecosystem concepts and their applications to natural and managed ecosystems.

385 Biotechnology and Genetic Engineering (3:3:0) Prerequisites: BIOL 311; CHEM 211, 212; MATH 110 or 113. Emphasizes theory and applications, including significance and societal implications of biotechnology applied to medicine, agriculture, and environment.

402 Applied and Industrial Microbiology (3:3:0) Prerequisites: BIOL 213, 305, 306; CHEM 211, 212; or permission of instructor. Biology of microorganisms of ecological and industrial significance. Includes food production, spoilage and preservation, fermentation technology, waste disposal, water purification, biodeterioration, and decomposition.

403 Techniques in Applied and Industrial Microbiology (1:0:3) Prerequisites: BIOL 213, 305, 306; CHEM 211, 212. Corequisite: BIOL 402, or permission of instructor. Lab exercises illustrate basic and applied methodologies, including isolation of commercially useful strains. Discusses production and purification of industrial products.

404 Medical Microbiology (3:3:0) Prerequisites: BIOL 305 and 306. Basic principles of infectious diseases caused by bacteria and viruses. Discusses genetics and molecular mechanisms of pathogenicity.

405 Microbial Genetics (4:3:3) Prerequisites: BIOL 305 and 306. Study of structure and function of bacterial DNA, emphasizing mechanisms of gene transfer, expression and regulation. Introduces DNA repair, mutation, and life cycles of bacteriophage.

406 Microbial Physiology and Metabolism (4:3:3) Prerequisites: BIOL 305 and 306. Study of complexity and diversity of microbial physiology and metabolism with emphasis on bacteria. Nutrition, growth, transport, and anabolic and catabolic processes are emphasized. Laboratory includes quantification of cellular macromolecules, enzyme purification and kinetics, column chromatography, and bacterial responses to environmental stimuli.

407 Microbial Diversity (4:3:3) Prerequisites: BIOL 305 and 306. Studies effect of microorganisms on ecological and medical phenomena. Stresses evolution of microbial species, biochemical cycling, and species interactions. Laboratory stresses use of cultural, biochemical, and phylogenetic methods to study microbial isolation, metabolism, and identification.

411 Advanced General Genetics (3:3:0) Prerequisites: 2.00 or better in BIOL 311, or permission of instructor. Topics include quantitative genetics, extrachromosomal inheritance, and special techniques such as mutation screening, developmental genetics, cancer genetics, behavior genetics, evolutionary genetics, and ethics of genetic technology.

417 Selected Topics in Molecular and Cellular Biology (1–4:0–3:0–6). Prerequisite: BIOL 311 or 482, or permission of instructor. Study of current topics in molecular and cellular biology. Lecture, laboratory. Topics vary. May be repeated for credit.

418 Current Topics in Microbiology (3:3:0) Prerequisites: BIOL 305 and 306. Study of current topics in microbiology. Topics vary. May be repeated for credit.

420 Vaccines (3:3:0). Prerequisite: BIOL 305/306. Immunology, virology, and microbiology of vaccines. Classical and new generation vaccine practices and strategies. Current and future vaccines.

421 Genetics of Human Diseases (3:3:0) Prerequisite: BIOL 311. Emphasizes strategies used for identification of genes involved in human genetic diseases. Both monogenic and complex human genetic diseases, as well as principles of genetic screening and counseling, will be presented.

422 Stem Cell Biology and Regenerative Medicine (3:3:0) Prerequisite: BIOL 311. A broad overview of the biological principles governing stem cell populations. The functional roles stem cells play in regulating normal development and contributing to disease-state pathologies. An examination of the therapeutic potential of stem cells through “regenerative medicine.”

425 Human Physiology (3:3:0) Prerequisite: BIOL 213, 303, or permission of instructor. Organ system approach to study of homeostasis, including cardiovascular, respiratory, renal, digestive, endocrine, and nervous system functions.

433 Selected Topics in Plant Biology (1–4:1–4:0–6) Prerequisite: BIOL 304, or permission of instructor. Lecture or field course in botany. Topic varies with instructor’s specialty.

440 Field Biology (1–4:0–2:3–9) Prerequisites: BIOL 303, 304, and 60 credits, or permission of instructor. Directed field studies emphasizing ecology and behavior. Topics vary but include design of field manipulations, data collection and analysis, and introduction to organisms of study site. Students bear cost of required field trips. May be repeated once with permission of department chair. Total limit for 440, 495, and 497 is 6 credits toward 44 credits required for BS, and only 4 credits toward 32 credits for BA, not to exceed 4 credits in any one semester.

446 Environmental Physiology (3:3:0) Prerequisite: BIOL 326, or permission of instructor. Physiological responses of animals to environmental factors and changes in natural environment. Topics include biorhythms and adaptation to temperature, high pressure, and altitude. Emphasis on vertebrates.

449 Marine Ecology (3:3:0) Prerequisite: BIOL 307 and BIOL/GEOL 309, or permission of instructor. Plants and animals of marine environments and physical and chemical conditions that affect their existence.

452 Immunology (3:3:0) Prerequisites: BIOL 213, 305, 306, and 311; or permission of instructor. Topics include structure and function of immunoglobulins, role of cell-mediated immunity, protective role of immune system, and disease and injury related to malfunctions of immune system. s

453 Immunology Laboratory (1:0:3) Prerequisite or corequisite: BIOL 452. Techniques relevant to BIOL 452, including enzyme-linked immunoabsorbant assay, immunodiffusion, protein electrophoresis, and immune fixation.

459 Fungi and Ecosystems (3:3:0) Prerequisite: BIOL 304, course in microbiology, or permission of instructor. Considers impact of fungi on ecosystems in terms of biogeochemical cycling, primary and secondary production, and regulating community structure and populations of individual species through their activities as symbionts and parasites. Discusses role of fungi in ameliorating pollutants produced by anthropogenic activities.

465 Histology (4:3:3) Prerequisites: BIOL 303 and 60 credits, or permission of instructor. Microscopic structure of animal tissues and organs, with emphasis on vertebrates.

471 Evolution (3:3:0) Prerequisite: BIOL 311, or permission of instructor. Process of evolution emphasizing role of genetics, properties of populations, and population differentiations. s

472 Introductory Animal Behavior (3:3:0) Prerequisites: BIOL 213, 303, or permission of instructor and 60 credits. Corequisite: BIOL 473. Study of mechanisms, functions, and evolution of behavior.

473 Introductory Laboratory in Animal Behavior (1:0:3) Corequisite: BIOL 472. Field or laboratory study in animal behavior with emphasis on mechanisms, functions, and evolution of behavior. Stresses experimental design and analysis of data. Writing-intensive laboratory.

482 Introduction to Molecular Genetics (3:3:0) Prerequisites: BIOL 213, 305, and 306, or permission of instructor. Basic concepts of structure and function of genetic material at molecular level.

483 General Biochemistry (4:4:0) Prerequisites: BIOL 213; CHEM 313, 314; or permission of instructor. Structure and function of proteins, carbohydrates, and lipids. Enzymology, and metabolism and its control.

484 Eukaryotic Cell Biology (3:3:0) Prerequisites: BIOL 311, 483; MATH 110 or 113; or permission of instructor. Structure and function of cell membranes and organelles with regard to cellular transport, sorting, compartmentalization, signaling, motility, and cell division.

485 Eukaryotic Cell Biology Laboratory (1:0:3) Corequisite: BIOL 484 or permission of instructor. Laboratory experiments using cell biology techniques, including microscopy, spectrophotometry, centrifugation, chromatography, and electrophoresis.

486 Molecular Biology and Biotechnology Laboratory (2:0:6) Prerequisites: BIOL 385 or 482. Introduction to theory, techniques and practices used in modern molecular biotechnology laboratories.

492 Senior Seminar (1:1:0) Prerequisites: BIOL 307 and 311, and 90 credits. Capstone course. f,s

493 Honors Research in Biology (1:0:0) Prerequisite: admission to the Biology Honors Program. Laboratory or field investigation under supervisor’s guidance.

494 Honors Seminar in Biology (1:1:0) Prerequisites: admission to department honors program, and permission of instructor. Weekly seminar course dealing with recent advances in biology. Topics selected from recent publications in field. May be repeated for credit six times. f,s

495 Directed Studies in Biology (1–2:0:0) Prerequisite: permission of instructor and department chair. Study of a topic not otherwise available to student. May involve reading assignments, tutorials, lectures, papers, presentations, or field or laboratory study, determined in consultation with instructor. May be taken for 1 to 2 credits and repeated once for a total of 2 credits. Total limit for 440, 495, and 497 is 6 credits toward 44 credits required for BS, and only 4 credits toward 32 credits for BA, not to exceed 4 credits in any one semester.

497 Special Problems in Biology (1–4:0:0) Prerequisites: 60 credits, and permission of instructor and department chair. Lab or field project leading to written report of research. Research and paper completed under instructor’s guidance. Total limit for 440, 495, and 497 is 6 credits toward 44 credits required for BS, and only 4 credits toward 32 credits for BA, not to exceed 4 credits in any one semester.

501 Microbial Diversity: An Organismal Approach (3:3:0) Prerequisite: undergraduate course in microbiology, or permission of instructor. In-depth study of nonpathogenic microbial world, emphasizing detection, enumeration, and classification of microorganisms; their physiological and evolutionary relationships; and biotechnological applications.

506 Selected Topics in Microbiology (1–4:1–3:0–6) Prerequisites: BIOL 305, 306, or permission of instructor. Topic depends on instructor’s specialty. May be repeated only with permission of department chair.

507 Selected Topics in Ecology (1–4:1–3:0–6) Prerequisite: course in ecology and permission of instructor. Topic depends on instructor’s specialty. May be repeated only with permission of department chair.

508 Selected Topics in Animal Biology (1–4:1–3:0–6) Prerequisite: BIOL 303, or permission of instructor. Topic depends on instructor’s specialty. May be repeated only with permission of department chair.

515 Introduction to Neurobiology (2:2:0) Prerequisite: completion of 60 credits, including PSYC 372; or BIOL 213 and 303. Introduction to neurobiology with an overview of embryological development of nervous system in evolutionary context. Regional and systems neuroanatomy is introduced by study of mammalian visual system with a comparative perspective.

516 Mammalian Neurobiology (3:2:3) Prerequisite: BIOL 515. Functional anatomy of mammal brains emphasizing regional and systems neuroanatomy of humans. Correlates with material from clinical neurology, where possible. Laboratory component includes brain dissections and clinical correlations.

518 Conservation Biology (3:3:0) Prerequisite: BIOL 307, 311, or equivalent. Introduction to science used to identify species in need of conservation, and techniques to manage and protect organisms.

520 Systematics in Complex Angiosperm Families (3:1:6) Prerequisite: BIOL 344 or 534, or permission of instructor. Morphology and speciation of more complex families such as Poaceae, Cyperaceae, and Asteraceae. Laboratory emphasizes identification of specimens, and acquaintance with taxonomic literature.

532 Animal Behavior (3:3:0) Prerequisite: permission of instructor. Ecological aspects of animal behavior.

533 Selected Topics in Plant Biology (1–4:1–3:0–6) Prerequisite: BIOL 304, or permission of instructor. Topic depends on instructor’s specialty. May be repeated only with permission of department chair.

534 Advanced Plant Taxonomy (3:1:6) Prerequisite: course in plant taxonomy, or permission of instructor. Laboratories consist of field trips, and collection and identification of specimens.

535 Ancient Plants and their Environment (3:3:0) Prerequisite: BIOL 304, course in paleontology, or permission of instructor. Study of factors involved in origin, history, and extinction of fossil plants, including adaptations, paleoecology, and major geological events.

536 Ichthyology (4:3:3) Prerequisite: course in ecology or permission of instructor. Studies systematics, evolution, physiology, ecology, and behavior of fishes. Lab time used for field trips, practice in identifying species, and hands-on experience with lecture subjects.

537 Ornithology (4:2:6) Prerequisite: course in ecology, or permission of instructor. Study of evolution, systematics, physiology, ecology, and behavior of birds, emphasizing field work. as

538 Mammology (4:2:6) Prerequisite: course in ecology, or permission of instructor. Study of evolution, systematics, physiology, ecology, and behavior of mammals, emphasizing field work.

539 Herpetology (4:2:6) Prerequisite: course in ecology, or permission of instructor. Study of evolution, systematics, physiology, ecology, and behavior of amphibians and reptiles, emphasizing field work.

543 Tropical Ecosystems (4:3:3) Prerequisite: course in ecology, or permission of instructor. Terrestrial, aquatic, and marine ecosystems in tropics, emphasizing plant communities, plant-animal interactions, and role of humans in the tropics. Field trip to tropics required as part of laboratory.

546 Estuarine and Coastal Ecology (4:3:3) Prerequisite: course in ecology, and permission of instructor. Emphasizes marine biology of estuarine and coastal habitats of Chesapeake Bay region, and factors affecting distribution and abundance of organisms. Laboratory provides training in field measurement of physical and chemical parameters, and collection and identification of local organisms. Extended field trips made to mid-Atlantic sites. sum

547 Terrestrial Plant Ecology (4:3:3) Prerequisite: course in ecology. Considers community organization, development, productivity, and mineral cycling; interactions between plants and competitors; herbivores; and environmental factors, especially light, water, and soil. Field work and laboratory emphasize data collection and statistical analysis.

553 Advanced Topics in Immunology (3:3:0) Prerequisite: BIOL 452, or permission of instructor. Comprehensive study of immunologic mechanisms as they pertain to immunologic diseases and transplantation.

556 Advanced Topics in Microbial Physiology and Metabolism (3:3:0) Prerequisite: BIOL 305, 306, or permission of instructor. Comprehensive study of microorganisms including growth, nutrition, transport, autotrophic and heterotrophic metabolism, regulation, and differentiation.

559 Fungi and Ecosystems (3:3:0) Prerequisite: BIOL 304 or a course in microbiology, or permission of instructor. Considers impact of fungi on ecosystems in terms of their effects on biogeochemical cycling, primary and secondary production, and regulating community structure and populations of individual species through their activities as symbionts and parasites. Discusses role of fungi in ameliorating pollutants produced by anthropogenic activities.

561 Comparative Animal Physiology (3:3:0) Prerequisite: BIOL 326, or permission of instructor. Detailed study of selected physiological systems of invertebrates and vertebrates, emphasizing current research.

563 Virology (3:3:0) Prerequisite: BIOL 482, or permission of instructor. Fundamental concepts of nature of viruses, virus classification, cultivation, and biochemistry. Emphasizes bacteriophage and animal viruses. f

564 Techniques in Virology (1:0:3). Prerequisites: BIOL 563, virology, and entrance into the PhD/biosciences or MS/biology program; or permission of instructor. Basic techniques of animal virus propagation, isolation, and quantitation.

566 Cancer Genomics (3:3:0) Prerequisite: course in genetics or biochemistry. Review of modern concepts in cancer biology including taxonomy of human tumors, common cancer syndromes, and genome instability. Genetic and molecular studies of tumor cell proliferation, migration, invasion, and death.

568 Advanced Topics in Molecular Genetics (3:3:0) Prerequisite: BIOL 482, or permission of instructor. Comprehensive study of regulatory mechanisms controlling gene expression in viruses, prokaryotes, and eukaryotes, emphasizing current research.

572 Human Genetics (3:3:0) Prerequisite: BIOL 311, or permission of instructor. Inheritance of humans emphasizing current problems, including genetic control of metabolic diseases, effects of radiation and chemical agents in environment, and directed genetic change.

573 Developmental Genetics (3:3:0) Prerequisite: BIOL 311, or permission of instructor. Genetic approaches to problem of eukaryotic development, emphasizing current research on regulation of gene enzyme systems.

574 Population Genetics (3:3:0) Prerequisites: BIOL 307 and 311, or permission of instructor. Genetic structure and dynamics of populations, both real and ideal.

575 Selected Topics in Genetics (1–4:1–3:0–6) Prerequisite: BIOL 311, or permission of instructor. Different topics in different years, including molecular, developmental, physiological, and classical genetics, emphasizing current problems and research. May be repeated once with permission of department chair.

576 Microbial Ecology of Soils (3:3:0) Prerequisites: BIOL 305, 306, or permission of instructor. Detection, identification, and physiological role of microorganisms in soils from root zone to deep subsurface. Emphasizes interactions of microorganisms, viruses through protests, and their functions in soil.

577 Biogeochemistry: A Global Perspective (3:3:0) Prerequisites: introductory courses in ecology and chemistry, or permission of instructor. Structure and function of ecosystems, their interactions as components of landscapes, and contributions to global environment. Emphasizes biogeochemical cycles of natural, disturbed, and managed ecosystems, and their integration at landscape and global level as related to current ecological problems such as transfer of nonpoint source pollutants, atmospheric deposition, stratospheric ozone depletion, and global change.

578 Mutation, DNA Repair, and Environmental Contamination (3:3:0) Prerequisites: BIOL 307 and 311. Overview of relationship between environmental contamination and genetic damage. Covers types of contamination that result in mutations, and molecular mechanisms of DNA damage and repair.

579 Molecular Evolution and Conservation Genetics (3:3:0) Prerequisite: BIOL 311. Corequisite: BIOL 471, or permission of instructor. Evolution of genes and gene families at molecular level, including gene duplication and divergence, positive and negative selection, genetic drift, and molecular clocks. Also includes selected applications in conservation genetics, such as molecular phylogenetics and estimates of population size.

580 Computer Applications for the Life Sciences (3:3:0) Prerequisites: 12 credits of biology and one year of college mathematics, or permission of instructor. Studies computer use in biological sciences. Combines lectures, supervised exercises on mainframe and microcomputers. Students present seminar on advanced application, and complete project using computer to fulfill major assignment associated with another course or employment.

583 General Biochemistry (4:4:0) Prerequisites: BIOL 213; CHEM 313, 314; or permission of instructor. Structure and function of proteins, carbohydrates and lipids, enzymology, and metabolism and its controls. Emphasizes chemistry of nitrogen compounds.

585 Eukaryotic Cell Biology Laboratory (1–2:0–1:3–6) Prerequisites:BIOL 484 or BIOL 682, or permission of instructor. Selected topics of laboratory procedures used in the study of eukaryotic cells. May be repeated one time with permission of program director.

587 Soil Ecology (3:3:0) Prerequisite: introductory course in general ecology or environmental science, or permission of instructor. Introduction to physical, chemical, and biological processes that govern development of soils and their ecological functions. Emphasizes central role that plants, microbes, and animals play in soil processes. Provides some training in system of soil classification and current methods to study soils.

588 Global Changes in Climate and Ecology (3:3:0) Prerequisites: introductory courses in general ecology or environmental science, or permission of instructor. Focuses on global-level changes that influence ecology. Introduces climate system—past, present, and future—emphasizing links between ecological systems and changes in climate, land use, and element cycling. Topics include responses of forests, oceans to climate change; effects of elevated carbon dioxide on plants; effects of ultraviolet radiation on aquatic systems; salt marsh responses to sea level rise; global eutrophication; desertification; carbon sequestration; and public policy implications of global change science.

589 Teaching Practicum (1:0:3) Prerequisites: permission of instructor, chair, and course coordinator (if any). Experience teaching biology in laboratory or in field under supervision of faculty member. Undergraduate assists instructor. May be repeated once.

607/EVPP 607 Fundamentals of Ecology (3:3:0) Overview of concepts in physiological, population, community, and ecosystem ecology. Restricted to graduate students with little or no background in ecology.

608 Topics in Biology (1–4:1–4:0–9) Prerequisite: employment or anticipated employment as science teacher. Not available for credit toward MS in biology, or PhD in environmental science and public policy. Inservice course to strengthen and update teacher’s knowledge of biology. Topics include organismal biology, cell biology, ecology, microbiology, or genetics. May be repeated for credit with permission of department chair.

610 Bioremediation: Theory and Applications (3:3:0) Prerequisites: course in microbiology and organic chemistry or biochemistry, or permission of instructor. Provides basis for understanding proper application of bioremedial technologies to treatment for hazardous wastes. Includes evaluation of data to determine successful treatment.

611 Techniques in Environmental Microbiology (2:0:4) Prerequisite: laboratory course in microbiology, or permission of instructor. Open first to those enrolled in BIOL 610. Laboratory exercises illustrate techniques to demonstrate microbial degradation, detection of microbes, isolation, and evaluation of physiological and genetic characteristics.

622 Methods and Principles of Animal Taxonomy (3:1:6) Prerequisite: course in evolution, or permission of instructor. Theoretical basis of techniques in animal classification, emphasizing practical application to laboratory problem dealing with a particular animal group.

640 Environmental Biology (3:3:0) Prerequisite: course in ecology, or permission of instructor. Patterns of climate and weather, tectonics, soil formation, and surface water and groundwater movements.

643 Microbial Ecology (4:3:3) Prerequisite: course in microbiology, or permission of instructor. Study of relationships between microorganisms and their natural environment, and methodology for observing their natural environment and biochemical activities in that environment.

648 Population Ecology (3:3:0) Prerequisite: course in ecology or permission of instructor. Survey of ecological models and theory. Topics include population growth and regulation; competition; predator-prey, herbivore-plant, and parasite-host interactions; mutualism; and metapopulation ecology.

649 Biological Resource Management (3:3:0) Prerequisite: course in ecology, or permission of instructor. Applies modern ecological theories and methods to biological resource management in developing and developed countries. Explores problems in achieving optimum productivity of specific resources and application of systems analysis.

665 Environmental Hazards to Human Health (3:3:0) Prerequisites: courses in animal physiology and organic chemistry, or permission of instructor. Health effects of chemical contaminants of air, water, and food resulting from industrialized society. Includes identifying, evaluating, and controlling hazards.

666 Human Genetics Concepts for Health Care (4:4:0) Prerequisites: BS degree or enrollment in accelerated MS program. Course in cell or molecular biology. Not available to students who have taken BIOL 572. Principles of genetically determined diseases with emphasis on clinical aspects of these diseases, genetic counseling, and laboratory methods used in human genetics. Extended studies students preparing to enter medical or dental school are welcome.

668 Advanced Techniques in Molecular Biology (4:2:6) Prerequisite: BIOL 568, or permission of instructor. Experimental studies using current methods for purification and characterization of biologically important compounds. Provides training for research in molecular biology.

669 Pathogenic Microbiology (3:3:0) Prerequisites: courses in microbiology and biochemistry. Molecular mechanisms of bacterial pathogenicity, and immune response in infectious diseases.

670 Environmental Law for Biologists (3:3:0) Prerequisite: course in ecology, environmental biology, or permission of instructor. Study of laws and regulatory issues such as National Environmental Policy Act and Clean Water and Clean Air Acts. Emphasizes critical evaluation of alternatives to unresolved issues in environmental policies.

680 Experimental Design and Analysis for the Life Sciences (4:3:3) Prerequisite: course in biostatistics, or permission of instructor. Advanced course in applying probability and statistics to research in life sciences. Examples drawn from environmental, medical, physiological, genetic, and chemical biology.

682 Advanced Eukaryotic Cell Biology (3:3:0). Prerequisites: BIOL 483, CHEM 313, 314; or permission of instructor. Structure and function of biomembranes, cytoskeleton, and transport systems. Also discusses protein trafficking, cell cycle, and cell adhesion molecules.

690 Introduction to Graduate Studies in Biology (2:2:0) Required of all new MS students in biology. f

691 Current Topics in Biology (1–4:1–3:0–6) May be repeated for credit.

692 Seminar in Biology (1:1:0) Topics vary. May be repeated for credit.

693 Directed Studies in Biology (1–8:0:0) Prerequisites: permission of instructor, chair, and graduate committee. May not be used to fulfill explicit undergraduate prerequisites for graduate work. Study of topic not otherwise available in graduate program. May involve any combination of reading assignments, tutorials, lectures, papers, presentations, or laboratory or field study, determined in consultation with instructor.

695 Seminar in Molecular, Microbial, and Cellular Biology (1:1:0) Review and discussion of recent literature in specialized area. Includes student presentations. May be repeated for credit.

715 Microbial Physiology (3:3:0). Prerequisites: undergraduate lecture/lab course in microbiology, and course in biochemistry. Comprehensive study of functioning of microbial cells, with emphasis on pathogens. Stresses growth, transport, cell-to-cell signaling, biofilm formation, antibiotic resistance, and secondary metabolites.

718 Techniques in Microbial Pathogenesis (3:0:3). Prerequisites: admission to biosciences PhD or biology MS program, and permission of instructor. Laboratory based class in which students perform current techniques in microbial pathogenesis.

720 Microbial Metabolism (3:3:0). Prerequisites: undergraduate lecture/lab course in microbiology, and course in biochemistry. Discussions of catabolic and anabolic pathways of bacterial pathogens, and regulation and integration of these pathways.

745 Environmental Toxicology (3:3:0) Prerequisites: courses in ecology and physiology, or permission of instructor. Study of nature, distribution, and interaction of toxic chemicals released into the environment. Emphasizes effects on nonhuman biota, detection and fate of chemicals, and implications for government regulation.

793 Research in Biology (1–3:0:0) Prerequisites: 8 graduate credits in BIOL, and permission of instructor and chair. Library, laboratory, or field investigation under supervisor’s guidance. May be repeated for total 3 credits.

798 Master’s Research Project (1–3:0:0) Prerequisites: permission of instructor and department chair. Students who take BIOL 793 may not receive more than 6 credits total for both BIOL 793 and 798. Experimental or theoretical research project chosen and completed under guidance of graduate faculty member. Comprehensive report acceptable to student’s advisory committee is required. Graded S/NC.

799 Thesis (1–6:0:0) Prerequisites: 8 graduate credits in BIOL, and permission of instructor and department chair. Students who take BIOL 793 may not receive more than 6 credits total for both BIOL 793 and 799. Thesis research under direction of supervisor. Graded S/NC.

800 Studies for the Doctor of Philosophy in Education (variable credit) Prerequisite: admission to PhD in education program to study in biology. Program of study designed by student’s discipline director and approved by student’s doctoral committee. Students participate in research of discipline director, and produce paper reporting original contributions. Paper presented in subsequent PhD summer seminar. Enrollment may be repeated.

See EVPP, Environmental Science and Public Policy, for additional related course work.