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Mass Spectrometry, Chromatography and Electrophoresis

Perkin Elmer BioXPRESSIONT Biomarker Platform via a Special Collaborative Effort

"The Perkin Elmer BioXPRESSIONT Biomarker Platform with Proteomic Signature Technology (PST) is avialable to CAPMM scientists in our pending CAP/CLIA laboratory through a special collaborative arrangement., PerkinElmer's unique biomarker enrichment and pattern recognition approach, sets BioXPRESSION apart from all other technologies. The BioXPRESSION platform combines powerful technologies from PerkinElmer and our partners: including a carrier-protein biomarker enrichment with novel membrane chromatography, the JANUS high throughput, automated, liquid handling platform to increase productivity, the exceptional high resolution detection using prOTOFT 2000 MALDI O-TOF mass spectrometry as well as powerful, dedicated, biomarker analysis capability software. " -Perkin Elmer Brochure
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Thermo Finnegan LTQ Linear Ion Trap Mass Spectrometer

"The Thermo Finnigan™ LTQ™ two dimensional (2D) linear ion trap mass spectrometer, with its
unique features, represents a major leap in ion trap technology from the traditional 3D quadrupole ion traps which have been a reliable tool for structural identification in complex matrices. The 2D linear ion trap in the LTQ is comprised of four parallel hyperbolic shaped rods, segmented into three sections. Ions are trapped radially in a radio frequency (RF) electric field and axially in a static electric field using DC voltages. Application of appropriate voltages to all three segments generates a homogenous field throughout the trapping region. The unique geometry of this device inherently increases the ion storage capacity while producing efficient ion detection. To maximize
detection of the increased number of trapped ions a mechanism for optimized ejection and detection was designed into the LTQ. Mass analysis using the Finnigan LTQ involves ejecting the trapped ions in the radial direction through the two parallel slots in the center section of the linear
ion trap. Two highly efficient detectors are optimally placed on either side of the trap to maximize sensitivity." - Thermo Finnegan Brochure
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Agilent Technologies 1100 Series Nanoflow Pump System

"The nanoflow pump uses a unique solvent delivery technology optimized for nanoliter-per-minute flows and features EFC (Electronic Flow Control) with active feedback and real time flow adjustment. First developed and implemented on the Agilent 1100 Series nanoflow pump, EFC is the gold standard for robust and reliable nanoflow performance and delivers the precise flow and gradient performance necessary for retention time reproducibility and stable ion generation essential for high sensitivity nanospray MS performance. " - Agilent Product Brochure
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PrinCE 700: The integrated Series High Performance Capillary Electrophoresis

"The PrinCE 700 series is a powerful integrated Capillary Electro Chromatography system with a very sensitive Diode Array Detector (DAD). It is fully automated, flexible, modular and suitable for almost any application. Thanks to the original modularity of the PrinCE system, it is still easy to couple to any external CE detector, or to Mass Spectrometer (MS). The PrinCE 700 series also offers the possibility for external pressure up to 10 bars and is standard supplied with samples and buffers cooling. The integrated systems can handle up to 32 (or optional 40) samples without interference of the operator, while still maintaining 10 (or optional 5) buffer vials. Any combination of six segments (sample/buffer type) can be used. The operator can exchange the segments easily without needing any tools. " - Prince Technologies Product Borchure
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