CAPMM

The Center for Applied Proteomics and Molecular Medicine is directed by Dr. Lance Liotta and Dr. Emanuel Petricoin III. Drs. Liotta and Petricoin were recently appointed to the George Mason faculty. Dr. Liotta, chief of the National Cancer Institute's Laboratory of Pathology, begins his tenure in May 2005. Dr. Petricoin, formerly with the Food and Drug Administration, joined the university earlier this month. They also hold research appointments at Inova Fairfax Hospital.

The Center has formed a unique partnership between George Mason and Inova Health System. George Mason University-Inova Health System Translational Research Centers is a joint initiative to coordinate multiple programs to implement proteomics, nanotechnology, and genomics research in cancer, metabolic syndrome, cardiopulmonary diseases, and neurodegenerative and liver diseases. This initiative comprises the research efforts of three shared centers: the Center for Applied Proteomics and Molecular Medicine; the Center for Biomedical Genomics; and the Center for the Study of Genomics of Liver Diseases. Inova and George Mason have combined efforts to recruit internationally renowned scientists, such as Lance Liotta and Emanuel Petricoin III, to work closely with clinical investigators from Inova.

Research in the Center will focus on the discovery and identification of biomarkers—biological indicators of cellular function in body fluids—for early disease detection and risk assessment, and the analysis of molecular pathways in diseased tissue to determine individualized and targeted treatment for patients. Results of the research will then be translated directly into patient management and care through clinical research and innovative clinical trials, with a vision toward creating a new paradigm to personalize medical treatment, resulting in a positive impact on public health.

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