Gene Therapy course (1 credit) will cover general principles of modern therapeutic approaches to treat inherited human diseases and cancer. Topics discussed in course includes a review of basic mechanisms and approaches in gene therapy, compilations of current clinical trial efforts, methods of gene delivery, immune therapeutics, oncolytic virus therapeutics, antisense therapeutics as well as ethical considerations in all these novel methods of therapy.

Enterprise Hall 278

Wednesdays 3:40 pm - 6:50 pm (Session A) - May 23rd is the first class

SYLLABUS 417

LECTURE 1

LECTURE 2

LECTURE 3

LECTURE 4

LECTURE 5

Graduate GENE THERAPY 1 Credit, Summer2007 (BIOL692)

Robinson Hall A101

Tuesdays 3:40 PM -6:50 PM (Session A) - May 22nd is the first class

SYLLABUS 692

LECTURE 1

LECTURE 2

LECTURE 3

LECTURE 4

LECTURE 5

• Undergraduate Honor Seminar 1 Credit, Fall 2006
  
    Structure of the research paper
    Citation index
    Mad Cow Disease
    Lecture 4
  Doctor Born's lecture
  
• Biol/BIOS seminar in Molecular and Microbiology ENGINEERED ANTIBODIES: DESIGN AND IMPLEMENTATION, 1 credit, SPRING 2007
  Syllabus
• Ancha's introductory lecture
  
• Biol 572 Human Genetics, 3 credits, FALL 2006
  Course Plan
  Lecture 1
  Lecture 2
  Lecture 3
  Lecture 4
  Lecture 5
  Lecture 6
  Lecture 7
  Lecture 8
  Lecture 9
  Lecture 10
  Lecture 11


• Biol 575 Cancer Genomics 3 Credits Spring 2007
  
  HUMAN TUMORS -- epidemiology, classification, conventional treatment. Clonal selection in human tumors. Metastasis as a product of cell evolution. Tumor suppressor genes and oncogenes. Cancer syndromes and other types of cancer predisposition.
  Instability of genome as a fundamental feature of a cancer cell. Types of mutations, LOH and LOI. Cancer- associated polymorhisms.
  How the new cancer related gene can be cloned and characterized. A review of the strategies in pre-genomic and post-genomic eras. Signaling pathways damaged or short-circuited in human tumors. RB genes network, cyclines, CDKs, CDKIs. Receptors and RTKs, SMADs, RAS-cascade, PTEN, NF1 etc. Extracellular matrix signaling, hypoxia, angiogenesis-related pathways and VHL. Differentiation-related pathways in leukemias and lymphomas. P53 as guardian of genome; BRCA1 and BRCA2 genes. Genome instability diseases as precondition for cancer. HNPCC, AT, XP, Bloom, Fanconi, Werner syndromes and underlying genes. Programmed cell death. Experimental cancer therapies
   Lecture 1
    Lecture 2
  Dr. Dan Cox guest lecture on stem cells in cancer
    Lecture 3
    Lecture 4
    Lecture 5
    Lecture 6
    Lecture 7
    Lecture 8
    Lecture 9
    Lecture 10
    Lecture 11
  Lecture 12
  SYLLABUS 2007
  
  
• Biol 693/BIOS742 Biotechnology 3 Credits, Spring 2006
    Lecture 1
    Lecture 2
    Lecture 3
    Lecture 4
    Lecture 5
    Lecture 6
    Lecture 7
  
  
• Biol 213 Cell structure and Function (undergrade) Spring 2006
   Lecture 1
    Lecture 2
    Lecture 3
    Lecture 4
    Lecture 5
    Lecture 6
    Lecture 7
    Lecture 8
    Lecture 9
    Lecture 10
    Lecture 11
    Lecture 12
    Lecture 13
    Lecture 14
    Lecture 15
    Lecture 16
  
  
• Biol/BIOS seminar in Molecular and Microbiology MOLECULAR DRUGS: ACTION AND DESIGN, 1 credit, FALL 2004
  

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