Research Interests:

We are interested in looking into a puzzle of molecular pathways in human cells. As this topic includes EVERYTHING, we are trying to concentrate on the most interesting pieces of this puzzle — pathways related to human diseases. Well, we are mostly working with human cancers and obesity. If genes cloned by us will be found to be involved in other interesting pathways — we are not going to be very disappointed.

Yes, we are also doing "classical" genomics. Publicly available databases are treasure troves full of undiscovered diamonds. We are not going to miss it.

ONGOING PROJECTS:

• KCNRG as a tumor suppressor gene
• Ectopic synthesis of melanin in adipose from morbidly obese subjects
• A role of pannexins in the development of the astrocytic tumors
• A role of excessive adipose in the development of the Fibrosis in the patients with Non-Alcoholic SteatoHepatitis (NASH)
• Gene Expression Patterns in the Hepatic Tissue and in the Visceral Adipose Tissue of the Patients with Non-Alcoholic Fatty Liver Disease
• Meta-Analysis of the Clinical Parameters of the Patients with Metabolic Syndrome
• Adipokines and pro-Inflammatory Cytokines in Non-Alcoholic Fatty Liver Disease

SOME NEWS ON OBESITY RESEARCH

Indeed, we found some interesting genes. Please follow THE LINK and view some of current results published in Obesity Surgery Journal :-)

SOME NEWS ON BIOINFORMATICS RESEARCH

1. "Transcription factor binding site (TFBS) prediction in the complete vertebrate genomes"
2. Small Interference (si) RNAs with High Specificity to the Target: a Systematic Approach to Design by CRM Algorithm"
3. OVARIAN CARCINOMA microarraying study : CERTOLI - LEYDIG Tumor (previously uncharacterized)
4. Potential regulatory SNPs in promoters of human genes:
   A systematic approach Published in Molecular and Cellular Probes.
5. In Silico Search for Natural Antisense Transcripts Reveals its Differential Expression in Human Tumors (download PDF)